Frances Xavier Cabrini Day is observed in Colorado every first Monday of October, celebrating the contributions of Frances Xavier Cabrini, an Italian-born Roman Catholic nun who dedicated much of her life to serving Italian immigrants in the United States. Instituted in 2020 as a replacement for Columbus Day, this state holiday honors Cabrini, the first U.S. citizen to be canonized by the Roman Catholic Church. Cabrini founded the Missionary Sisters of the Sacred Heart of Jesus and established schools, orphanages, and hospitals in cities such as New York, Chicago, and Denver. The inaugural Cabrini Day was celebrated on October 5, 2020, primarily through virtual events due to the COVID-19 pandemic. This holiday is significant as it is the first paid state holiday in the U.S. to honor a woman, reflecting a shift in how certain historical figures are commemorated.