Los Santos Uprising Day is observed in Panama every November 10, commemorating the beginning of the country's struggle for independence from Spain in 1821. The day marks the event known as the Grito de La Villa de los Santos, where Rufina Alfaro, a young woman from a village near Los Santos, led an anti-Spanish uprising by rallying Panamanians to seize Spanish barracks without bloodshed, shouting “Viva la Libertad.” This uprising significantly influenced Panama's independence movement, despite some disdain from certain regions. The holiday is part of Panama's Fiestas Patrias, celebrating the nation's independence struggles, and is widely celebrated with colorful parades, folk music, dance, and cultural events throughout the country.