National Vaccination Day, also known as National Immunization Day, is observed in India every March 16. This date commemorates the first administration of the oral polio vaccine in 1995, which initiated the Pulse Polio immunization campaign aimed at eradicating poliomyelitis. The day celebrates healthcare workers who deliver vaccines and emphasizes the importance of immunization for public health. On this occasion, the government and relevant stakeholders organize vaccination drives, awareness campaigns, and events to educate the public and combat misinformation about vaccinations. India has seen significant success in its immunization efforts, including being declared poliomyelitis-free in 2014 and working towards the elimination of rubella and measles. The significance of vaccination became particularly evident during the COVID-19 pandemic, prompting preparations for a vaccination campaign well in advance of vaccine authorization.