Heterotaxy Syndrome Awareness Day is observed worldwide every May 4. Established in 2014, this day aims to highlight Heterotaxy syndrome, a rare genetic condition that affects the development and placement of major internal organs, leading to potential severe health issues. The day serves to provide resources and support for affected families and pays tribute to those who have passed away due to the condition, as well as to healthcare professionals working to improve patient outcomes. Heterotaxy, also known as situs ambiguus, involves an abnormal arrangement of internal organs, which can result in various complications, including heart defects and respiratory issues. The observance encourages education about the condition and fosters a community for those impacted by it.