TSC Global Awareness Day is observed worldwide every May 15 to promote awareness of tuberous sclerosis complex (TSC), a rare genetic condition characterized by the growth of benign tumors in the brain and other vital organs. The day was launched in 2013 by Tuberous Sclerosis Complex International (TSCi), a consortium that supports TSC patients and facilitates research collaboration. Activities on this day include awareness campaigns, fundraisers, seminars, and webinars organized by TSCi and various TSC organizations globally. Participants are encouraged to engage in events, wear blue clothing or ribbons, and use social media hashtags like #TSCGlobalAwarenessDay to foster discussions about TSC. The goals of the observance include providing hope to TSC patients, promoting research, and improving access to care and treatments.