Global Porphyria Day is observed worldwide every May 18 to educate the public about porphyria, a group of rare diseases affecting the nervous system and skin. It was established by the Global Porphyria Advocacy Coalition (GPAC), which represents national patient groups focused on all types of porphyria. The day aims to promote understanding of the eight types of porphyria, which result from enzyme deficiencies affecting heme production, leading to symptoms such as abdominal pain, skin fragility, and photosensitivity. Participants can engage by wearing purple to show support, sharing information on social media with hashtags like #GlobalPorphyriaDay and #PurpleForPorphyria, and advocating for better access to diagnosis and treatment. Additionally, individuals are encouraged to contact local governments to light landmarks in purple on this day.