Generalized Pustular Psoriasis (GPP) Awareness Day is observed worldwide every August 13. Established in 2025 by the National Psoriasis Foundation in collaboration with Boehringer Ingelheim, the day aims to highlight GPP, a rare and potentially life-threatening form of psoriasis. GPP is characterized by the sudden appearance of sterile pustules on large areas of the body, often accompanied by symptoms such as fatigue, fever, and intense itching. The awareness day focuses on educating healthcare providers about GPP and supporting those living with the condition. GPP flares can pose serious health risks, necessitating effective management strategies, including medications that suppress inflammation and targeted treatments like spesolimab.