International SCN2A Awareness Day is observed worldwide every February 24 to highlight disorders caused by mutations in the SCN2A gene, which include early-onset epilepsy, autism spectrum disorder, and various neurological problems. The date was specifically chosen because the SCN2A gene is located on the long (q) arm of chromosome 2 at position 24.3 (2/24). The day aims to provide support to individuals affected by SCN2A-related disorders and their families. Medical conditions linked to SCN2A mutations encompass a range of issues, such as intellectual disability, movement disorders, and sleep disorders. Mutations can lead to either gain of function or loss of function in sodium channels, resulting in different neurological symptoms. This observance is distinct from International SCN8A Awareness Day, which is celebrated on February 9 to address epilepsy related to mutations in the SCN8A gene.