National Dress in Blue Day is observed on the first Friday in March each year in the United States to raise awareness about colon cancer and its prevention. The day encourages participants to wear blue, symbolizing colon cancer, similar to how pink represents breast cancer. The initiative was started by Anita Mitchell, a colon cancer survivor, who aimed to honor those affected by the disease and promote awareness. Participants often make a donation to colon cancer awareness while wearing blue outfits. The Colon Cancer Alliance officially launched the campaign to encourage regular screenings, which can significantly reduce colon cancer deaths. There is also a suggestion to extend awareness efforts throughout the entire month of March, akin to National Breast Cancer Awareness Month in October.