Melanoma B-RAF Awareness Day is observed in the UK every May 26 as part of Melanoma Awareness Month. This day was launched in 2022 by Melanoma UK, a patient support and advocacy group, in collaboration with Novartis Pharmaceuticals UK Ltd. It aims to educate the public about B-RAF mutations that are involved in the development of melanoma, a dangerous type of skin cancer. The BRAF gene is the most common gene mutation in melanoma, with nearly half of all melanoma patients affected. On this day, individuals are encouraged to inquire about their B-RAF status and to share information on social media using hashtags like #MelanomaBRAFAwarenessDay. The initiative also highlights the existence of targeted therapies for BRAF-positive melanoma, which can improve treatment options for patients.