Cornelia De Lange Syndrome Awareness Day is observed on the second Saturday of May, with the next observance falling on May 9. This day was established to educate society about Cornelia De Lange Syndrome (CdLS), a rare genetic disorder also known as Bushy Syndrome or Amsterdam dwarfism, which presents a range of medical challenges that can vary in severity. The observance aims to raise awareness and eliminate the stigma faced by individuals and families affected by the syndrome. Symptoms of CdLS include small head size, below-average weight, intellectual development delays, and various physical abnormalities. The condition is diagnosed through clinical assessments and genetic testing, and it can be caused by different gene mutations. Treatment often involves a multidisciplinary approach to address the diverse medical needs of those affected.