National Prescription Drug Take Back Day is observed on the last Saturday of April and October, with the next event scheduled for October 25, 2025. This initiative, founded by the Drug Enforcement Administration (DEA) in 2010, aims to promote the safe disposal of expired or unused prescription medications to enhance community health and safety. Participants are encouraged to collect these medications and dispose of them properly at designated collection sites, which can be found on the DEA website. The event serves as a call to action for individuals, schools, and community organizations to partner and raise awareness about the importance of responsible drug disposal. It addresses critical issues such as drug misuse among youth and confusion among the elderly regarding medication management. The tagline "Keep them safe. Clean them out. Take them back." emphasizes the event's focus on safety and community well-being.