Microvillus Inclusion Disease Awareness Day, also known as MVID Awareness Day, is observed in New York on September 16. Established in 2017 by Assemblyman Ed Ra, this day was inspired by Tom and Melissa Onorato, who founded the TKO Strong Foundation after their son was diagnosed with MVID. The day aims to support families affected by this rare genetic disorder and to raise funds for research focused on finding a cure or improving treatment options. MVID, characterized by the absence of normal intestinal microvilli, leads to severe malabsorption and chronic diarrhea from infancy, necessitating lifelong intravenous feeding or intestinal transplants for survival. The observance highlights the importance of awareness and support for those impacted by this condition, which is extremely rare, with only a few hundred diagnosed cases.