World Duchenne Awareness Day is observed worldwide every September 7. This international observance is dedicated to Duchenne muscular dystrophy (DMD), a severe X-linked recessive genetic disorder primarily affecting males. The day aims to highlight the importance of early diagnosis and daily therapy for those affected by DMD, which is characterized by mutations in the dystrophin gene. Symptoms typically begin around age 4, leading to significant mobility challenges by age 12. The observance is celebrated under the patronage of the European Parliament and was designated as a United Nations observance in November 2023. Activities on this day focus on spreading information about physical therapy and treatments that can enhance the quality of life for individuals with DMD. Common complications associated with the condition include scoliosis, respiratory issues, and cardiomyopathy, with an average life expectancy of 26 years.