Usher Syndrome Awareness Day is observed worldwide every third Saturday of September. This day was created to highlight Usher syndrome, a rare genetic disorder that is the most common genetic cause of combined blindness and deafness, resulting from mutations in various genes. The syndrome is categorized into three subtypes based on the onset of hearing loss and the affected genes. The Usher Syndrome Coalition, a non-profit organization, promotes this awareness day and works to accelerate research while supporting individuals and families affected by the syndrome. Since 2015, efforts have been made to have Usher Syndrome Awareness Day recognized by the United States Congress, leading to proclamations from several states. Activities on this day include educating the public about Usher syndrome, donating to relevant organizations, and sharing information on social media using specific hashtags.