Bohring-Opitz Syndrome Awareness Day, also known as BOS Awareness Day, is observed worldwide every April 6. It was established in 2015 by Taylor Gurganus, co-founder and vice chair of the BOS Foundation, to support families affected by the rare genetic disorder Bohring-Opitz syndrome (BOS), which is caused by mutations in the ASXL1 gene. The day commemorates the formation of the first BOS Support Group on Facebook. Typical customs include wearing gold and denim awareness ribbons, participating in awareness events, and sharing information on social media using the hashtags #BohringOpitzSyndromeAwarenessDay and #BOSAwarenessDay. The BOS Foundation focuses on improving the lives of those affected through advocacy, education, and research.