World Ankylosing Spondylitis Day, also known as World AS Day, is observed worldwide on the first Saturday of May, moving to the next Saturday if May 1 falls on that date. Established by the Axial Spondyloarthritis International Federation (ASIF), this day aims to highlight ankylosing spondylitis (AS), a chronic inflammatory disease primarily affecting the spine and pelvis. Individuals typically participate by learning about the impact of AS, engaging in digital events hosted by ASIF and patient organizations, or organizing their own events. Supporters often wear a blue awareness ribbon and use social media hashtags like #WorldAnkylosingSpondylitisDay to spread information about the condition. AS affects millions globally, with early symptoms appearing between the ages of 20 and 30, and while there is no cure, various treatments are available to manage symptoms.